Inherited ventricular ectopy and sudden death in young German Shepherd dogs
نویسندگان
چکیده
منابع مشابه
Abnormal cardiac repolarization and impulse initiation in German shepherd dogs with inherited ventricular arrhythmias and sudden death.
OBJECTIVE We tested the hypothesis that delayed afterdepolarization (DAD)-associated rhythms in German shepherd dogs with reduced anteroseptal left ventricular (LV) sympathetic innervation derive from abnormal beta-adrenergic receptor effector coupling. METHODS AND RESULTS In anteroseptal LV midmyocardium of afflicted dogs, beta-receptor density was greater than that in normal dogs (P < .05),...
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By causing numerous changes in the cardiovascular system, ageing leads to a decreased threshold for clinical manifestation of heart disease. The aim of this study was to define the existence of cardiac structural and functional changes in healthy dogs of different age. Radiographic, electrocardiographic (ECG) and echocardiographic examinations of 20 clinically healthy German Shepherd dogs were ...
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متن کاملEchocardiographic indices in normal German shepherd dogs
Sixty clinically normal German shepherd dogs, 31 males and 29 females, ranging in age from 1 and 5 years and with a body weight ranging from 22 to 37.2 kg, were examined by the two-dimensional mode, M-mode, and Doppler echocardiography. In Doppler mode, the mitral valve flows were obtained, where the aim was to determine the velocity peaks and ratios of the E and A waves and the mitral E wave d...
متن کاملElectropharmacological characterization of cardiac repolarization in German shepherd dogs with an inherited syndrome of sudden death: abnormal response to potassium channel blockers.
OBJECTIVES This study sought to determine whether abnormal ventricular repolarization is implicated in cardiac arrhythmias of German shepherd dogs with inherited sudden death. BACKGROUND Moïse et al. (9) have identified German shepherd dogs that display pause-dependent lethal ventricular arrhythmias. METHODS Ventricular repolarization was studied both in vivo using electrocardiogram recordi...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1990
ISSN: 0735-1097
DOI: 10.1016/0735-1097(90)92323-t